In the field of gene therapy, scientists have been constantly searching for more precise methods to regulate therapeutic gene expression for on-demand drug delivery. At present, many successful therapies rely on the introduction of an exogenous gene, which functions within the body much like welding a new component onto a machine—once installed, it becomes difficult to adjust or remove at any ...

If a tumor is likened to an indestructible “fortress”, then oncolytic bacteria can be regarded as fearless “warriors” launching an assault. Once the attack command is given, these “oncolytic bacterial warriors” act in an orderly and coordinated manner, launching a fierce offensive that ultimately breaches the “tumor fortress”.The hypoxic and immunosuppressive microenvironment within sol...

Global warming exacerbates the intensity of extreme precipitation, triggering flood-related disasters and posing severe challenges to the sustainable development of natural and social systems. On January 20, 2025, Professor Li Chao’s team from ECNU, published a pioneering study in Nature Communications titled “Increasing certainty in projected local extreme precipitation change.”Paper Link: ...

Recently, a research team led by Researcher Lu Weiqiang and Prof. Liu Mingyao from the School of Life Sciences, ECNU achieved a groundbreaking advancement in tumor immunotherapy. Their pioneering study has unveiled a novel mechanism through which HCAR1, a member of the G protein-coupled receptor (GPCR) family, facilitates tumor immune evasion by sensing lactate signals. This significant discove...

On November 28th, 2024, the China Association for Science and Technology announced the "Selected Projects in Phase II of the Excellence Action Plan of China’s Scientific and Technical Journals". The first English journal in the field of Anthropocene in China, Anthropocene Coasts, hosted by East China Normal University, has been successfully selected for the "High-Starting Point Journal in Phas...

The Bulk Photovoltaic Effect (BPVE) is a novel photovoltaic phenomenon observed in non-centrosymmetric materials. With its unique advantages, including angle-resolved sensitivity to light-polarization and the potential to surpass the Shockley-Queisser theoretical efficiency limit of pn-junction solar cells, the BPVE has emerged as a frontier and hotspot in photovoltaic research. On the other ha...

A team led by Professor Li Dali from the School of Life Sciences at East China Normal University (ECNU) has recently developed a novel, ultra-high activity, and miniaturized gene editing tool based on IscB, achieving efficient editing in mice for the first time. This groundbreaking research was published online in the prestigious international academic journal Molecular Cell on August 22, 2024,...

On July 15, 2024, the achievements made by ECNU’s scientific research team, composed of Du Bing, Liu Mingyao, and Li Dali from the School of Life Sciences, were published online in Cell, a top international journal, marking the first global report on the use of allogeneic universal CAR-T to treat rheumatic immune diseases.ECNU’s scientific research team composed of Du Bing, Liu Mingyao, and L...

The Institute of Electrical and Electronics Engineers (IEEE) Symposium on VLSI (Very-large-scale integration) Technology and Circuits, a highly regarded international forum in the field of semiconductor devices and processes, has recognized the groundbreaking research conducted by Professor Yan Cheng and her team from East China Normal University (ECNU). The team's latest findings, titled "Pola...